Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis

Regulating dietary fat absorption may impact progression of nonalcoholic fatty liver disease (NAFLD). Here, we asked if inducible inhibition of chylomicron assembly, as observed in intestine-specific microsomal triglyceride (TG) transfer protein knockout mice (Mttp-IKO), could retard NAFLD progressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Yan, Newberry, Elizabeth P., Brunt, Elizabeth M., Ballentine, Samuel J., Soleymanjahi, Saeed, Molitor, Elizabeth A., Davidson, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515302/
https://www.ncbi.nlm.nih.gov/pubmed/34563519
http://dx.doi.org/10.1016/j.jlr.2021.100123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515302/
https://www.ncbi.nlm.nih.gov/pubmed/34563519
http://dx.doi.org/10.1016/j.jlr.2021.100123

Ejemplares similares