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Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis
Regulating dietary fat absorption may impact progression of nonalcoholic fatty liver disease (NAFLD). Here, we asked if inducible inhibition of chylomicron assembly, as observed in intestine-specific microsomal triglyceride (TG) transfer protein knockout mice (Mttp-IKO), could retard NAFLD progressi...
Autores principales: | Xie, Yan, Newberry, Elizabeth P., Brunt, Elizabeth M., Ballentine, Samuel J., Soleymanjahi, Saeed, Molitor, Elizabeth A., Davidson, Nicholas O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515302/ https://www.ncbi.nlm.nih.gov/pubmed/34563519 http://dx.doi.org/10.1016/j.jlr.2021.100123 |
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