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Rapid Analysis of Biotherapeutics Using Protein A Chromatography Coupled to Orbitrap Mass Spectrometry

[Image: see text] Monoclonal antibodies (mAbs) and related products undergo a wide range of modifications, many of which can often be directly associated to culture conditions during upstream processing. Ideally, such conditions should be monitored and fine-tuned based on real-time or close to real-...

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Detalles Bibliográficos
Autores principales: Jakes, Craig, Füssl, Florian, Zaborowska, Izabela, Bones, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515350/
https://www.ncbi.nlm.nih.gov/pubmed/34585915
http://dx.doi.org/10.1021/acs.analchem.1c02365