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Current Approaches and Molecular Mechanisms for Directly Reprogramming Fibroblasts Into Neurons and Dopamine Neurons

Parkinson’s disease is mainly caused by specific degeneration of dopaminergic neurons (DA neurons) in the substantia nigra of the middle brain. Over the past two decades, transplantation of neural stem cells (NSCs) from fetal brain-derived neural stem cells (fNSCs), human embryonic stem cells (hESCs...

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Detalles Bibliográficos
Autores principales: Han, Fabin, Liu, Yanming, Huang, Jin, Zhang, Xiaoping, Wei, Chuanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515543/
https://www.ncbi.nlm.nih.gov/pubmed/34658841
http://dx.doi.org/10.3389/fnagi.2021.738529