Cargando…

Current Approaches and Molecular Mechanisms for Directly Reprogramming Fibroblasts Into Neurons and Dopamine Neurons

Parkinson’s disease is mainly caused by specific degeneration of dopaminergic neurons (DA neurons) in the substantia nigra of the middle brain. Over the past two decades, transplantation of neural stem cells (NSCs) from fetal brain-derived neural stem cells (fNSCs), human embryonic stem cells (hESCs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Fabin, Liu, Yanming, Huang, Jin, Zhang, Xiaoping, Wei, Chuanfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515543/ https://www.ncbi.nlm.nih.gov/pubmed/34658841 http://dx.doi.org/10.3389/fnagi.2021.738529

Ejemplares similares

The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo
por: Chen, Qingfa, et al.
Publicado: (2020)

Mechanistic Insights Into MicroRNA-Induced Neuronal Reprogramming of Human Adult Fibroblasts
por: Lu, Ya-Lin, et al.
Publicado: (2018)

Mechanisms for multiple activity modes of VTA dopamine neurons
por: Oster, Andrew, et al.
Publicado: (2015)

Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation
por: Chen, Ming, et al.
Publicado: (2015)

Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells
por: Liu, Xinjian, et al.
Publicado: (2012)

Salsolinol modulation of dopamine neurons
por: Xie, Guiqin, et al.
Publicado: (2013)

Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors
por: Colasante, Gaia, et al.
Publicado: (2019)

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?
por: Drouin-Ouellet, Janelle, et al.
Publicado: (2017)

How to reprogram human fibroblasts to neurons
por: Xu, Ziran, et al.
Publicado: (2020)

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons
por: Luo, Chongyuan, et al.
Publicado: (2019)

Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
por: Tang, Yu, et al.
Publicado: (2017)

Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons
por: Oh, Seung-ick, et al.
Publicado: (2014)

Mechanisms for the Modulation of Dopamine D(1) Receptor Signaling in Striatal Neurons
por: Nishi, Akinori, et al.
Publicado: (2011)

Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups
por: Ferrari, Diana C., et al.
Publicado: (2012)

Protocol Optimization for Direct Reprogramming of Primary Human Fibroblast into Induced Striatal Neurons
por: Kraskovskaya, Nina, et al.
Publicado: (2023)

Behavioral Modulation by Spontaneous Activity of Dopamine Neurons
por: Ichinose, Toshiharu, et al.
Publicado: (2017)

Subcellular proteomics of dopamine neurons in the mouse brain
por: Hobson, Benjamin D, et al.
Publicado: (2022)

Editorial: Dopamine Neuron Diversity in Circuits and Diseases
por: Poulin, Jean-Francois, et al.
Publicado: (2022)

Regeneration of the cerebral cortex by direct chemical reprogramming of macrophages into neuronal cells in acute ischemic stroke
por: Ninomiya, Itaru, et al.
Publicado: (2023)

Morphological evidence for dopamine interactions with pallidal neurons in primates
por: Eid, Lara, et al.
Publicado: (2015)

Dopamine neuron dependent behaviors mediated by glutamate cotransmission
por: Mingote, Susana, et al.
Publicado: (2017)

Presynaptic inhibition of dopamine neurons controls optimistic bias
por: Yamagata, Nobuhiro, et al.
Publicado: (2021)

Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum
por: Maltese, Marta, et al.
Publicado: (2021)

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
por: Treutlein, Barbara, et al.
Publicado: (2016)

Directly reprogrammed fragile X syndrome dorsal forebrain precursor cells generate cortical neurons exhibiting impaired neuronal maturation
por: Edwards, Nicole, et al.
Publicado: (2023)

Dissociable Effects of Dopamine on Neuronal Firing Rate and Synchrony in the Dorsal Striatum
por: Burkhardt, John M., et al.
Publicado: (2009)

Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release
por: Liu, Xiaojie, et al.
Publicado: (2022)

Temporal scaling of dopamine neuron firing and dopamine release by distinct ion channels shape behavior
por: Juarez, Barbara, et al.
Publicado: (2023)

Corrigendum: Morphological evidence for dopamine interactions with pallidal neurons in primates
por: Eid, Lara, et al.
Publicado: (2015)

Effects of Dopamine on the Immature Neurons of the Adult Rat Piriform Cortex
por: Coviello, Simona, et al.
Publicado: (2020)

Spiking and Membrane Properties of Rat Olfactory Bulb Dopamine Neurons
por: Korshunov, Kirill S., et al.
Publicado: (2020)

Dopamine neuron ensembles signal the content of sensory prediction errors
por: Stalnaker, Thomas A, et al.
Publicado: (2019)

Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons
por: Ducrot, Charles, et al.
Publicado: (2023)

Commentary: Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-off: A Direct Electrophysiological Comparison in Behaving Monkeys
por: Ang, Yuen-Siang, et al.
Publicado: (2015)

Very Low Efficiency of Direct Reprogramming of Astrocytes Into Neurons in the Brains of Young and Aged Mice After Cerebral Ischemia
por: Gresita, Andrei, et al.
Publicado: (2019)

Impact of Transcranial Direct Current Stimulation (tDCS) on Neuronal Functions
por: Das, Suman, et al.
Publicado: (2016)

Molecular Mechanisms for the Coupling of Endocytosis to Exocytosis in Neurons
por: Xie, Zhenli, et al.
Publicado: (2017)

Direct Reprogramming of Somatic Cells to Neurons: Pros and Cons of Chemical Approach
por: Mollinari, Cristiana, et al.
Publicado: (2021)

Dopamine activity in projection neurons regulates short‐lasting olfactory approach memory in Drosophila
por: Naganos, Shintaro, et al.
Publicado: (2022)

Direct neuronal reprogramming by temporal identity factors
por: Boudreau-Pinsonneault, Camille, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p3badls557g0mraph5qtps7s3t