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Receptor-selective interleukin-4 mutein attenuates laser-induced choroidal neovascularization through the regulation of macrophage polarization in mice

Macrophage polarization has been recognized as an important inflammatory regulator in choroidal neovascularization (CNV). However, the mechanisms regulating macrophage activation and polarization, as well as their effects on angiogenesis and CNV, have not yet been elucidated. IL-4 is implicated in m...

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Detalles Bibliográficos
Autores principales: Gao, Limo, Jiang, Wenmin, Liu, Haiying, Chen, Zhiheng, Lin, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515545/
https://www.ncbi.nlm.nih.gov/pubmed/34659513
http://dx.doi.org/10.3892/etm.2021.10801