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VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody

BACKGROUND: Neuropathic pain is a clinically relevant adverse effect of several anticancer drugs that markedly impairs patients’ quality of life and frequently leads to dose reduction or therapy discontinuation. The poor knowledge about the mechanisms involved in neuropathy development and pain chro...

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Detalles Bibliográficos
Autores principales: Micheli, Laura, Parisio, Carmen, Lucarini, Elena, Vona, Alessia, Toti, Alessandra, Pacini, Alessandra, Mello, Tommaso, Boccella, Serena, Ricciardi, Flavia, Maione, Sabatino, Graziani, Grazia, Lacal, Pedro Miguel, Failli, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515680/
https://www.ncbi.nlm.nih.gov/pubmed/34649573
http://dx.doi.org/10.1186/s13046-021-02127-x