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Circ_0045714/miR-331-3p interaction affects IL-1β-evoked human articular chondrocyte injury through regulating PIK3R3 in a ceRNA regulatory cascade

BACKGROUND: Osteoarthritis (OA) is characterized by joint pain and joint function limitation. Hsa_circ_0045714 (circ_0045714) is a novel OA-related circular RNA. However, its repertoire remains to be further clarified in joint chondrocytes. METHODS: RNA and protein expression levels and inflammatory...

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Detalles Bibliográficos
Autores principales: Ding, Ran, Zhou, Jinsong, Xu, Jianguo, Lu, Huajie, Zhang, Tingting, Xiang, Xiong, Shi, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515683/
https://www.ncbi.nlm.nih.gov/pubmed/34649564
http://dx.doi.org/10.1186/s13018-021-02738-2