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Circ_0045714/miR-331-3p interaction affects IL-1β-evoked human articular chondrocyte injury through regulating PIK3R3 in a ceRNA regulatory cascade
BACKGROUND: Osteoarthritis (OA) is characterized by joint pain and joint function limitation. Hsa_circ_0045714 (circ_0045714) is a novel OA-related circular RNA. However, its repertoire remains to be further clarified in joint chondrocytes. METHODS: RNA and protein expression levels and inflammatory...
Autores principales: | Ding, Ran, Zhou, Jinsong, Xu, Jianguo, Lu, Huajie, Zhang, Tingting, Xiang, Xiong, Shi, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515683/ https://www.ncbi.nlm.nih.gov/pubmed/34649564 http://dx.doi.org/10.1186/s13018-021-02738-2 |
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