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Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most intractable tumors in the world due to its high rate of recurrence and heterogeneity. Liver cancer initiating cells also called cancer stem cells (CSCs) play a critical role in resistance against typical therapy and high tumor-initiating...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515748/ https://www.ncbi.nlm.nih.gov/pubmed/34649567 http://dx.doi.org/10.1186/s12943-021-01435-2 |