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Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse
The complement alternative pathway (AP) is tightly regulated and changes in two important AP components, factor B (FB) and factor H (FH) are linked to severe dengue in humans. Here, a mouse model of dengue was investigated to define the changes in FB and FH and assess the utility of this model to st...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515863/ https://www.ncbi.nlm.nih.gov/pubmed/33410734 http://dx.doi.org/10.1099/jgv.0.001547 |