Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse

The complement alternative pathway (AP) is tightly regulated and changes in two important AP components, factor B (FB) and factor H (FH) are linked to severe dengue in humans. Here, a mouse model of dengue was investigated to define the changes in FB and FH and assess the utility of this model to st...

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Detalles Bibliográficos
Autores principales: Cabezas-Falcon, Sheila, Norbury, Aidan J., Hulme-Jones, Jarrod, Klebe, Sonja, Adamson, Penelope, Rudd, Penny A., Mahalingam, Suresh, Ong, Li-Ching, Alonso, Sylvie, Gordon, David L., Carr, Jillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515863/
https://www.ncbi.nlm.nih.gov/pubmed/33410734
http://dx.doi.org/10.1099/jgv.0.001547

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