cAMP Receptor Protein Positively Regulates the Expression of Genes Involved in the Biosynthesis of Klebsiella oxytoca Tilivalline Cytotoxin

Klebsiella oxytoca is a resident of the human gut. However, certain K. oxytoca toxigenic strains exist that secrete the nonribosomal peptide tilivalline (TV) cytotoxin. TV is a pyrrolobenzodiazepine that causes antibiotic-associated hemorrhagic colitis (AAHC). The biosynthesis of TV is driven by enz...

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Detalles Bibliográficos
Autores principales: Rodríguez-Valverde, Diana, León-Montes, Nancy, Soria-Bustos, Jorge, Martínez-Cruz, Jessica, González-Ugalde, Ricardo, Rivera-Gutiérrez, Sandra, González-y-Merchand, Jorge A., Rosales-Reyes, Roberto, García-Morales, Lázaro, Hirakawa, Hidetada, Fox, James G., Girón, Jorge A., De la Cruz, Miguel A., Ares, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515920/
https://www.ncbi.nlm.nih.gov/pubmed/34659176
http://dx.doi.org/10.3389/fmicb.2021.743594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515920/
https://www.ncbi.nlm.nih.gov/pubmed/34659176
http://dx.doi.org/10.3389/fmicb.2021.743594

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