Cargando…

cAMP Receptor Protein Positively Regulates the Expression of Genes Involved in the Biosynthesis of Klebsiella oxytoca Tilivalline Cytotoxin

Klebsiella oxytoca is a resident of the human gut. However, certain K. oxytoca toxigenic strains exist that secrete the nonribosomal peptide tilivalline (TV) cytotoxin. TV is a pyrrolobenzodiazepine that causes antibiotic-associated hemorrhagic colitis (AAHC). The biosynthesis of TV is driven by enz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodríguez-Valverde, Diana, León-Montes, Nancy, Soria-Bustos, Jorge, Martínez-Cruz, Jessica, González-Ugalde, Ricardo, Rivera-Gutiérrez, Sandra, González-y-Merchand, Jorge A., Rosales-Reyes, Roberto, García-Morales, Lázaro, Hirakawa, Hidetada, Fox, James G., Girón, Jorge A., De la Cruz, Miguel A., Ares, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515920/ https://www.ncbi.nlm.nih.gov/pubmed/34659176 http://dx.doi.org/10.3389/fmicb.2021.743594

Ejemplares similares

Two Type VI Secretion Systems of Enterobacter cloacae Are Required for Bacterial Competition, Cell Adherence, and Intestinal Colonization
por: Soria-Bustos, Jorge, et al.
Publicado: (2020)

Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment
por: Hering, Nina A., et al.
Publicado: (2019)

Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities
por: Unterhauser, Katrin, et al.
Publicado: (2019)

The Two-Component System CpxRA Represses Salmonella Pathogenicity Island 2 by Directly Acting on the ssrAB Regulatory Operon
por: León-Montes, Nancy, et al.
Publicado: (2022)

Cytotoxin-producing Klebsiella oxytoca in the preterm gut and its association with necrotizing enterocolitis
por: Paveglio, Sara, et al.
Publicado: (2020)

The Flp type IV pilus operon of Mycobacterium tuberculosis is expressed upon interaction with macrophages and alveolar epithelial cells
por: Alteri, Christopher J., et al.
Publicado: (2022)

Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline
por: Dornisch, Elisabeth, et al.
Publicado: (2017)

Molecular typing of cytotoxin-producing Klebsiella oxytoca isolates by 16S-23S internal transcribed spacer PCR
por: Soltan Dallal, M.M., et al.
Publicado: (2019)

Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence
por: Chimal-Cázares, Fernando, et al.
Publicado: (2020)

H-NS Nucleoid Protein Controls Virulence Features of Klebsiella pneumoniae by Regulating the Expression of Type 3 Pili and the Capsule Polysaccharide
por: Ares, Miguel A., et al.
Publicado: (2016)

The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis
por: Wolff, Hendrik, et al.
Publicado: (2018)

The Two-Component System CpxRA Negatively Regulates the Locus of Enterocyte Effacement of Enterohemorrhagic Escherichia coli Involving σ(32) and Lon protease
por: De la Cruz, Miguel A., et al.
Publicado: (2016)

Whole Genome Sequencing of Pediatric Klebsiella pneumoniae Strains Reveals Important Insights Into Their Virulence-Associated Traits
por: Flores-Valdez, Mauricio, et al.
Publicado: (2021)

Hypoxia Is Not a Main Stress When Mycobacterium tuberculosis Is in a Dormancy-Like Long-Chain Fatty Acid Environment
por: Del Portillo, Patricia, et al.
Publicado: (2019)

The Interaction of Klebsiella pneumoniae With Lipid Rafts-Associated Cholesterol Increases Macrophage-Mediated Phagocytosis Due to Down Regulation of the Capsule Polysaccharide
por: Ares, Miguel A., et al.
Publicado: (2019)

Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor
por: Ares, Miguel A., et al.
Publicado: (2017)

A NOTE ON THE SPECIFICITY OF CYTOTOXINS
por: Lambert, Robert A.
Publicado: (1914)

The Lack of the TetR-Like Repressor Gene BCG_2177c (Rv2160A) May Help Mycobacteria Overcome Intracellular Redox Stress and Survive Longer Inside Macrophages When Surrounded by a Lipid Environment
por: García-Morales, Lázaro, et al.
Publicado: (2022)

Transcriptional Profiling of Type II Toxin–Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967–HP0968 System
por: Cárdenas-Mondragón, María G., et al.
Publicado: (2016)

Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions
por: Kurabayashi, Kumiko, et al.
Publicado: (2017)

The Assembly of Flagella in Enteropathogenic Escherichia coli Requires the Presence of a Functional Type III Secretion System
por: Soria-Bustos, Jorge, et al.
Publicado: (2022)

The Coli Surface Antigen CS3 of Enterotoxigenic Escherichia coli Is Differentially Regulated by H-NS, CRP, and CpxRA Global Regulators
por: Ares, Miguel A., et al.
Publicado: (2019)

The Transcription of Flagella of Enteropathogenic Escherichia coli O127:H6 Is Activated in Response to Environmental and Nutritional Signals
por: Avelino-Flores, Fabiola, et al.
Publicado: (2022)

The EcpD Tip Adhesin of the Escherichia coli Common Pilus Mediates Binding of Enteropathogenic E. coli to Extracellular Matrix Proteins
por: Mondal, Rajesh, et al.
Publicado: (2022)

The penetration of cytotoxins into malignant tumours.
por: Rowe-Jones, D. C.
Publicado: (1968)

Escherichia coli Subtilase Cytotoxin
por: Paton, Adrienne W., et al.
Publicado: (2010)

Infectious crystalline keratopathy associated with Klebsiella oxytoca
por: Chou, Timothy Y., et al.
Publicado: (2012)

Klebsiella oxytoca Endocarditis With Complete Heart Block
por: Ullah, Saad, et al.
Publicado: (2016)

Helicobacter pylori infection: is there circulating vacuolating cytotoxin A or cytotoxin-associated gene A protein?
por: Imoto, Ichiro, et al.
Publicado: (2022)

Naja naja oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic Three-Fingered Cytotoxins
por: Gasanov, Sardar E., et al.
Publicado: (2015)

Detection of a Putative TetR-Like Gene Related to Mycobacterium bovis BCG Growth in Cholesterol Using a gfp-Transposon Mutagenesis System
por: Otal, Isabel, et al.
Publicado: (2017)

Identification of Novel Potential Vaccine Candidates against Tuberculosis Based on Reverse Vaccinology
por: Monterrubio-López, Gloria P., et al.
Publicado: (2015)

Cytotoxins and immunotoxins for cancer therapy : clinical applications /
Publicado: (2005)

THE CULTIVATION OF TISSUES IN VITRO AS A METHOD FOR THE STUDY OF CYTOTOXINS
por: Lambert, Robert A., et al.
Publicado: (1911)

The Fis Nucleoid Protein Negatively Regulates the Phase Variation fimS Switch of the Type 1 Pilus Operon in Enteropathogenic Escherichia coli
por: Saldaña-Ahuactzi, Zeus, et al.
Publicado: (2022)

Structural and Functional Dissection of the Heterocyclic Peptide Cytotoxin Streptolysin S
por: Mitchell, Douglas A., et al.
Publicado: (2009)

Acute Infectious Purpura Fulminans Caused by Klebsiella oxytoca
por: Tsubouchi, Nobuhiko, et al.
Publicado: (2019)

Tuberculous shadow in Klebsiella oxytoca pneumonia: An unexpected denouement
por: Kinjo, Takeshi, et al.
Publicado: (2021)

Resource Allocation During the Transition to Diazotrophy in Klebsiella oxytoca
por: Waite, Christopher J., et al.
Publicado: (2021)

Molecular Origins of Transcriptional Heterogeneity in Diazotrophic Klebsiella oxytoca
por: Bashir, Tufail, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t84kechoislmqrt7ds1lo1p4f2