Structure‐Activity Relationship Studies of Hydantoin‐Cored Ligands for Smoothened Receptor

An underside binding site was recently identified in the transmembrane domain of smoothened receptor (SMO). Herein, we report efforts in the exploration of new insights into the interactions between the ligand and SMO. The hydantoin core in the middle of the parent compound was found to be highly co...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhou, Fang, Ding, Kang, Xue, Dongxiang, Zhu, Zhihao, Li, Cuixia, Li, Fei, Xu, Yueming, Xu, Fei, Le, Zhiping, Zhao, Suwen, Tao, Houchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515922/
https://www.ncbi.nlm.nih.gov/pubmed/34648230
http://dx.doi.org/10.1002/open.202100216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515922/
https://www.ncbi.nlm.nih.gov/pubmed/34648230
http://dx.doi.org/10.1002/open.202100216

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