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Structure‐Activity Relationship Studies of Hydantoin‐Cored Ligands for Smoothened Receptor
An underside binding site was recently identified in the transmembrane domain of smoothened receptor (SMO). Herein, we report efforts in the exploration of new insights into the interactions between the ligand and SMO. The hydantoin core in the middle of the parent compound was found to be highly co...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515922/ https://www.ncbi.nlm.nih.gov/pubmed/34648230 http://dx.doi.org/10.1002/open.202100216 |