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Shared Mutations in Emerging SARS-CoV-2 Circulating Variants May Lead to Reverse Transcription-PCR (RT-PCR)-Based Misidentification of B.1.351 and P.1 Variants of Concern

Reverse transcription-PCRs (RT-PCRs) targeting SARS-CoV-2 variant of concern (VOC) mutations have been developed to simplify their tracking. We evaluated an assay targeting E484K/N501Y to identify B.1.351/P1. Whole-genome sequencing (WGS) confirmed only 72 (59.02%) of 122 consecutive RT-PCR P.1/B.1....

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Detalles Bibliográficos
Autores principales: Losada, Carmen, Rico-Luna, Carla, Otero-Sobrino, Álvaro, Molero-Salinas, Andrea, Buenestado-Serrano, Sergio, Candela, Ana, Pérez-Lago, Laura, Muñoz, Patricia, Catalán, Pilar, de Viedma, Darío García
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515932/
https://www.ncbi.nlm.nih.gov/pubmed/34643437
http://dx.doi.org/10.1128/Spectrum.00816-21