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From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries

Since their inception, genome-wide association studies (GWAS) have identified more than a hundred thousand single nucleotide polymorphism (SNP) loci that are associated with various complex human diseases or traits. The majority of GWAS discoveries are located in non-coding regions of the human geno...

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Detalles Bibliográficos
Autores principales: Li, Binglan, Ritchie, Marylyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515949/
https://www.ncbi.nlm.nih.gov/pubmed/34659337
http://dx.doi.org/10.3389/fgene.2021.713230