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Predicting drug targets by homology modelling of Pseudomonas aeruginosa proteins of unknown function

The efficacy of antibiotics to treat bacterial infections declines rapidly due to antibiotic resistance. This problem has stimulated the development of novel antibiotics, but most attempts have failed. Consequently, the idea of mining uncharacterized genes of pathogens to identify potential targets...

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Detalles Bibliográficos
Autores principales: Babic, Nikolina, Kovacic, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516228/
https://www.ncbi.nlm.nih.gov/pubmed/34648550
http://dx.doi.org/10.1371/journal.pone.0258385