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A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6

BACKGROUND: The mitogen‐activated protein kinase (MAPK) pathway is highly associated with the progression and metastasis of various solid tumours. MAPK14, a core molecule of the MAPK pathway, plays vital roles in the colorectal cancer (CRC). Recent studies have shown that circRNAs can affect tumour...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Zhou, Jiahui, Zhang, Chuan, Chen, Ranran, Sun, Qingyang, Yang, Peng, Peng, Chaofan, Tan, Yuqian, Jin, Chi, Wang, Tuo, Ji, Jiangzhou, Sun, Yueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516360/
https://www.ncbi.nlm.nih.gov/pubmed/34709743
http://dx.doi.org/10.1002/ctm2.613