Targeting miR‐126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells

BACKGROUND: Myelodysplastic syndrome (MDS) arises from a rare population of aberrant hematopoietic stem and progenitor cells (HSPCs). These cells are relatively quiescent and therefore treatment resistant. Understanding mechanisms underlying their maintenance is critical for effective MDS treatment....

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Detalles Bibliográficos
Autores principales: Wang, Huafeng, Sun, Jie, Zhang, Bin, Zhao, Dandan, Tong, Hongyan, Wu, Herman, Li, Xia, Luo, Yingwan, Dong, Dan, Yao, Yiyi, McDonald, Tinisha, Stein, Anthony S., Al Malki, Monzr M., Pichiorri, Flavia, Carlesso, Nadia, Kuo, Ya‐Huei, Marcucci, Guido, Li, Ling, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516361/
https://www.ncbi.nlm.nih.gov/pubmed/34709739
http://dx.doi.org/10.1002/ctm2.610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516361/
https://www.ncbi.nlm.nih.gov/pubmed/34709739
http://dx.doi.org/10.1002/ctm2.610

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