A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

Zinc and ring finger 3 (ZNRF3) is a transmembrane E3 ubiquitin ligase that targets Wnt receptors for ubiquitination and lysosomal degradation. Previously, we showed that dephosphorylation of an endocytic tyrosine motif (4Y motif) in ZNRF3 by protein tyrosine phosphatase receptor-type kappa (PTPRK) p...

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Detalles Bibliográficos
Autores principales: Kim, Minseong, Reinhard, Carmen, Niehrs, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
https://www.ncbi.nlm.nih.gov/pubmed/34590584
http://dx.doi.org/10.7554/eLife.70885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
https://www.ncbi.nlm.nih.gov/pubmed/34590584
http://dx.doi.org/10.7554/eLife.70885

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