Atractylenolide III alleviates sepsis-mediated lung injury via inhibition of FoxO1 and VNN1 protein

PURPOSE: To evaluate the influence of atractylenolide (Atr) III on sepsis-induced lung damage. METHODS: We constructed a mouse sepsis model through cecal ligation and puncture. These mice were allocated to the normal, sepsis, sepsis + Atr III-L (2 mg/kg), as well as Atr III-H (8 mg/kg) group. Lung i...

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Detalles Bibliográficos
Autores principales: Fu, Ji-ding, Gao, Chun-hui, Li, Shi-wei, Tian, Yan, Li, Shi-cheng, Wei, Yi-er, Xian, Le-wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516425/
https://www.ncbi.nlm.nih.gov/pubmed/34644770
http://dx.doi.org/10.1590/ACB360802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516425/
https://www.ncbi.nlm.nih.gov/pubmed/34644770
http://dx.doi.org/10.1590/ACB360802

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