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Deficiency in the frequency and function of Tr1 cells in IgAV and the possible role of IL-27

OBJECTIVE: Type 1 regulatory T (Tr1) cells are involved in the pathogenesis of numerous immune-mediated diseases. However, little is known about whether and how Tr1 cells affect the development of IgA vasculitis (IgAV). We aimed to investigate this question in IgAV patients. METHODS: . Tr1 cells in...

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Detalles Bibliográficos
Autores principales: Pan, Lu, Wang, Jinghua, Liu, Jinxiang, Guo, Lishuang, Yang, Sirui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516516/
https://www.ncbi.nlm.nih.gov/pubmed/33280050
http://dx.doi.org/10.1093/rheumatology/keaa752