The DNA Repair Enzyme XPD Is Partially Regulated by PI3K/AKT Signaling in the Context of Bupivacaine-Mediated Neuronal DNA Damage

Bupivacaine, a local anesthetic widely used for regional anesthesia and pain management, has been reported to induce neuronal injury, especially DNA damage. Neurons employ different pathways to repair DNA damage. However, the mechanism underlying bupivacaine-mediated DNA damage repair is unclear. A...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Zeng, Lei, Luo, Jiaming, Li, Ji, Lai, Luying, Xu, Shiyuan, Liu, Zhongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516563/
https://www.ncbi.nlm.nih.gov/pubmed/34659643
http://dx.doi.org/10.1155/2021/9925647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516563/
https://www.ncbi.nlm.nih.gov/pubmed/34659643
http://dx.doi.org/10.1155/2021/9925647

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