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Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation

Inhibition of human ether-a-go-go-related gene (hERG) potassium channel is responsible for acquired long QT syndromes, which leads to life-threatening cardiac arrhythmia. A multikinase inhibitor, vandetanib, prolongs the progression-free survival time in advanced medullary thyroid cancer. However, v...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Luo, Dan, Li, Fang, Li, Zhiyi, Gao, Xiaoli, Qiao, Jie, Wu, Lin, Li, Miaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516564/
https://www.ncbi.nlm.nih.gov/pubmed/34659631
http://dx.doi.org/10.1155/2021/3520034