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Logic and lineage impacts on functional transcription factor deployment for T-cell fate commitment
Transcription factors are the major agents that read the regulatory sequence information in the genome to initiate changes in expression of specific genes, both in development and in physiological activation responses. Their actions depend on site-specific DNA binding and are largely guided by their...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Biophysical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516641/ https://www.ncbi.nlm.nih.gov/pubmed/33838137 http://dx.doi.org/10.1016/j.bpj.2021.04.002 |