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Logic and lineage impacts on functional transcription factor deployment for T-cell fate commitment

Transcription factors are the major agents that read the regulatory sequence information in the genome to initiate changes in expression of specific genes, both in development and in physiological activation responses. Their actions depend on site-specific DNA binding and are largely guided by their...

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Detalles Bibliográficos
Autor principal: Rothenberg, Ellen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516641/
https://www.ncbi.nlm.nih.gov/pubmed/33838137
http://dx.doi.org/10.1016/j.bpj.2021.04.002