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NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
N-myc downstream-regulated gene 1 (NDRG1) is a key regulator that interacts with many classic tumor signaling pathways, including some molecules downstream of the epidermal growth factor receptor (EGFR). However, whether NDRG1 is involved in the mechanism of resistance to cetuximab (CTX), the first...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516652/ https://www.ncbi.nlm.nih.gov/pubmed/34385595 http://dx.doi.org/10.1038/s41388-021-01962-8 |