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NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer

N-myc downstream-regulated gene 1 (NDRG1) is a key regulator that interacts with many classic tumor signaling pathways, including some molecules downstream of the epidermal growth factor receptor (EGFR). However, whether NDRG1 is involved in the mechanism of resistance to cetuximab (CTX), the first...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Huang, Ling, Jia, Hongtao, Aikemu, Batuer, Zhang, Sen, Shao, Yanfei, Hong, Hiju, Yesseyeva, Galiya, Wang, Chenxing, Li, Shuchun, Sun, Jing, Zheng, Minhua, Ma, Junjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516652/
https://www.ncbi.nlm.nih.gov/pubmed/34385595
http://dx.doi.org/10.1038/s41388-021-01962-8