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Epididymal Fat-Derived Sympathoexcitatory Signals Exacerbate Neurogenic Hypertension in Obese Male Mice Exposed to Early Life Stress

Previously, we have shown that male mice exposed to maternal separation and early weaning (MSEW)—a mouse model of early life stress—display increased mean arterial pressure compared with controls when fed a high-fat diet. As the stimulation of sensory nerves from fat has been shown to trigger the ad...

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Detalles Bibliográficos
Autores principales: Dalmasso, Carolina, Leachman, Jacqueline R., Ghuneim, Sundus, Ahmed, Nermin, Schneider, Eve R., Thibault, Olivier, Osborn, Jeffrey L., Loria, Analia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516729/
https://www.ncbi.nlm.nih.gov/pubmed/34601958
http://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17298