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Quantification of kappa opioid receptor ligand potency, efficacy and desensitization using a real-time membrane potential assay
We explored the utility of the real-time FLIPR Membrane Potential (FMP) assay as a method to assess kappa opioid receptor (KOR)-induced hyperpolarization. The FMP Blue dye was used to measure fluorescent signals reflecting changes in membrane potential in KOR expressing CHO (CHO-KOR) cells. Treatmen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516733/ https://www.ncbi.nlm.nih.gov/pubmed/34536757 http://dx.doi.org/10.1016/j.biopha.2021.112173 |