A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAF(V600) wild-type colorectal cancer

PURPOSE: We hypothesised that plasticity in signal transduction may be a mechanism of drug resistance and tested this hypothesis in the setting of cetuximab resistance in patients with KRAS/NRAS/BRAF(V600) wild-type colorectal cancer (CRC). METHODS: A multiplex antibody-based platform was used to st...

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Detalles Bibliográficos
Autores principales: Georgiou, Alexandros, Stewart, Adam, Vlachogiannis, Georgios, Pickard, Lisa, Valeri, Nicola, Cunningham, David, Whittaker, Steven R., Banerji, Udai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516765/
https://www.ncbi.nlm.nih.gov/pubmed/34462871
http://dx.doi.org/10.1007/s13402-021-00628-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516765/
https://www.ncbi.nlm.nih.gov/pubmed/34462871
http://dx.doi.org/10.1007/s13402-021-00628-7

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