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A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAF(V600) wild-type colorectal cancer
PURPOSE: We hypothesised that plasticity in signal transduction may be a mechanism of drug resistance and tested this hypothesis in the setting of cetuximab resistance in patients with KRAS/NRAS/BRAF(V600) wild-type colorectal cancer (CRC). METHODS: A multiplex antibody-based platform was used to st...
Autores principales: | Georgiou, Alexandros, Stewart, Adam, Vlachogiannis, Georgios, Pickard, Lisa, Valeri, Nicola, Cunningham, David, Whittaker, Steven R., Banerji, Udai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516765/ https://www.ncbi.nlm.nih.gov/pubmed/34462871 http://dx.doi.org/10.1007/s13402-021-00628-7 |
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