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Integrin activation is an essential component of SARS-CoV-2 infection

SARS-CoV-2 infection depends on binding its spike (S) protein to angiotensin-converting enzyme 2 (ACE2). The S protein expresses an RGD motif, suggesting that integrins may be co-receptors. Here, we UV-inactivated SARS-CoV-2 and fluorescently labeled the envelope membrane with octadecyl rhodamine B...

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Detalles Bibliográficos
Autores principales: Simons, Peter, Rinaldi, Derek A., Bondu, Virginie, Kell, Alison M., Bradfute, Steven, Lidke, Diane S., Buranda, Tione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516859/
https://www.ncbi.nlm.nih.gov/pubmed/34650161
http://dx.doi.org/10.1038/s41598-021-99893-7