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Morphodynamics facilitate cancer cells to navigate 3D extracellular matrix

Cell shape is linked to cell function. The significance of cell morphodynamics, namely the temporal fluctuation of cell shape, is much less understood. Here we study the morphodynamics of MDA-MB-231 cells in type I collagen extracellular matrix (ECM). We systematically vary ECM physical properties b...

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Detalles Bibliográficos
Autores principales: Eddy, Christopher Z., Raposo, Helena, Manchanda, Aayushi, Wong, Ryan, Li, Fuxin, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516896/
https://www.ncbi.nlm.nih.gov/pubmed/34650167
http://dx.doi.org/10.1038/s41598-021-99902-9