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Global gene expression analysis of systemic sclerosis myofibroblasts demonstrates a marked increase in the expression of multiple NBPF genes

Myofibroblasts are the key effector cells responsible for the exaggerated tissue fibrosis in Systemic Sclerosis (SSc). Despite their importance to SSc pathogenesis, the specific transcriptome of SSc myofibroblasts has not been described. The purpose of this study was to identify transcriptome differ...

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Detalles Bibliográficos
Autores principales: Abignano, Giuseppina, Hermes, Heidi, Piera-Velazquez, Sonsoles, Addya, Sankar, Del Galdo, Francesco, Jimenez, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516909/
https://www.ncbi.nlm.nih.gov/pubmed/34650102
http://dx.doi.org/10.1038/s41598-021-99292-y