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Introducing dorsoventral patterning in adult regenerating lizard tails with gene-edited embryonic neural stem cells

Lizards regenerate amputated tails but fail to recapitulate the dorsoventral patterning achieved during embryonic development. Regenerated lizard tails form ependymal tubes (ETs) that, like embryonic tail neural tubes (NTs), induce cartilage differentiation in surrounding cells via sonic hedgehog (S...

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Detalles Bibliográficos
Autores principales: Lozito, Thomas P., Londono, Ricardo, Sun, Aaron X., Hudnall, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516916/
https://www.ncbi.nlm.nih.gov/pubmed/34650077
http://dx.doi.org/10.1038/s41467-021-26321-9