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Introducing dorsoventral patterning in adult regenerating lizard tails with gene-edited embryonic neural stem cells
Lizards regenerate amputated tails but fail to recapitulate the dorsoventral patterning achieved during embryonic development. Regenerated lizard tails form ependymal tubes (ETs) that, like embryonic tail neural tubes (NTs), induce cartilage differentiation in surrounding cells via sonic hedgehog (S...
Autores principales: | Lozito, Thomas P., Londono, Ricardo, Sun, Aaron X., Hudnall, Megan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516916/ https://www.ncbi.nlm.nih.gov/pubmed/34650077 http://dx.doi.org/10.1038/s41467-021-26321-9 |
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