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Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

Breast cancer is the most common cancer in the world. Relapse and metastasis are important factors endangering the life of breast cancer patients, but the mechanism is still unclear. The stabilization of p53 is essential for preventing carcinogenesis, and ubiquitination is one of the main ways to re...

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Detalles Bibliográficos
Autores principales: Guo, Yafei, Li, Qin, Zhao, Gang, Zhang, Jie, Yuan, Hang, Feng, Tianyu, Ou, Deqiong, Gu, Rui, Li, Siqi, Li, Kai, Lin, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516922/
https://www.ncbi.nlm.nih.gov/pubmed/34650049
http://dx.doi.org/10.1038/s41419-021-04208-3