Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses

A key to enhance the low translatability of preclinical drug discovery are in vitro human three-dimensional (3D) microphysiological systems (MPS). Here, we show a new method for automated engineering of 3D human skeletal muscle models in microplates and functional compound screening to address the l...

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Detalles Bibliográficos
Autores principales: Alave Reyes-Furrer, Angela, De Andrade, Sonia, Bachmann, Dominic, Jeker, Heidi, Steinmann, Martin, Accart, Nathalie, Dunbar, Andrew, Rausch, Martin, Bono, Epifania, Rimann, Markus, Keller, Hansjoerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516940/
https://www.ncbi.nlm.nih.gov/pubmed/34650188
http://dx.doi.org/10.1038/s42003-021-02691-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516940/
https://www.ncbi.nlm.nih.gov/pubmed/34650188
http://dx.doi.org/10.1038/s42003-021-02691-0

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