Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease

Mitochondrial dysfunction and bioenergetics failure are common pathological hallmarks in Huntington’s disease (HD) and aging. In the present study, we used the YAC128 murine model of HD to examine the effects of mutant huntingtin on mitochondrial parameters related to aging in brain and skeletal mus...

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Detalles Bibliográficos
Autores principales: Bečanović, Kristina, Asghar, Muhammad, Gadawska, Izabella, Sachdeva, Shiny, Walker, David, Lazarowski, Eduardo. R., Franciosi, Sonia, Park, Kevin H. J., Côté, Hélène C. F., Leavitt, Blair R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516942/
https://www.ncbi.nlm.nih.gov/pubmed/34650085
http://dx.doi.org/10.1038/s41514-021-00079-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516942/
https://www.ncbi.nlm.nih.gov/pubmed/34650085
http://dx.doi.org/10.1038/s41514-021-00079-2

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