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MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells

The PIWI (P-element-induced wimpy testis)-interacting-RNA (piRNA) pathway plays a crucial role in the repression of TE (transposable element) expression via de novo DNA methylation in mouse embryonic male germ cells. Various proteins, including MIWI2 are involved in the process. TE silencing is ensu...

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Detalles Bibliográficos
Autores principales: Kojima-Kita, Kanako, Kuramochi-Miyagawa, Satomi, Nakayama, Manabu, Miyata, Haruhiko, Jacobsen, Steven E., Ikawa, Masahito, Koseki, Haruhiko, Nakano, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516955/
https://www.ncbi.nlm.nih.gov/pubmed/34650118
http://dx.doi.org/10.1038/s41598-021-98940-7