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MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells
The PIWI (P-element-induced wimpy testis)-interacting-RNA (piRNA) pathway plays a crucial role in the repression of TE (transposable element) expression via de novo DNA methylation in mouse embryonic male germ cells. Various proteins, including MIWI2 are involved in the process. TE silencing is ensu...
Autores principales: | Kojima-Kita, Kanako, Kuramochi-Miyagawa, Satomi, Nakayama, Manabu, Miyata, Haruhiko, Jacobsen, Steven E., Ikawa, Masahito, Koseki, Haruhiko, Nakano, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516955/ https://www.ncbi.nlm.nih.gov/pubmed/34650118 http://dx.doi.org/10.1038/s41598-021-98940-7 |
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