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INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants

Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine-induced immunity. Here we compared humoral and cellular responses against SARS-CoV-2 VOC in subjects immunized with the DNA vaccin...

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Detalles Bibliográficos
Autores principales: Andrade, Viviane M., Christensen-Quick, Aaron, Agnes, Joseph, Tur, Jared, Reed, Charles, Kalia, Richa, Marrero, Idania, Elwood, Dustin, Schultheis, Katherine, Purwar, Mansi, Reuschel, Emma, McMullan, Trevor, Pezzoli, Patrick, Kraynyak, Kim, Sylvester, Albert, Mammen, Mammen P., Tebas, Pablo, Joseph Kim, J., Weiner, David B., Smith, Trevor R. F., Ramos, Stephanie J., Humeau, Laurent M., Boyer, Jean D., Broderick, Kate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516974/
https://www.ncbi.nlm.nih.gov/pubmed/34650089
http://dx.doi.org/10.1038/s41541-021-00384-7