Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities

Defective pericyte-endothelial cell interaction in tumors leads to a chaotic, poorly organized and dysfunctional vasculature. However, the underlying mechanism behind this is poorly studied. Herein, we develop a method that combines magnetic beads and flow cytometry cell sorting to isolate pericytes...

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Detalles Bibliográficos
Autores principales: Meng, Ya-Ming, Jiang, Xue, Zhao, Xinbao, Meng, Qiong, Wu, Sangqing, Chen, Yitian, Kong, Xiangzhan, Qiu, Xiaoyi, Su, Liangping, Huang, Cheng, Wang, Minghui, Liu, Chao, Wong, Ping-Pui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517026/
https://www.ncbi.nlm.nih.gov/pubmed/34650057
http://dx.doi.org/10.1038/s41467-021-26259-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517026/
https://www.ncbi.nlm.nih.gov/pubmed/34650057
http://dx.doi.org/10.1038/s41467-021-26259-y

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