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Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities
Defective pericyte-endothelial cell interaction in tumors leads to a chaotic, poorly organized and dysfunctional vasculature. However, the underlying mechanism behind this is poorly studied. Herein, we develop a method that combines magnetic beads and flow cytometry cell sorting to isolate pericytes...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517026/ https://www.ncbi.nlm.nih.gov/pubmed/34650057 http://dx.doi.org/10.1038/s41467-021-26259-y |