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Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish—implications for neurodevelopmental disorders

Recent advances in the genetics of neurodevelopmental disorders (NDDs) have identified the transcription factor FOXP2 as one of numerous risk genes, e.g. in autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). FOXP2 function is suggested to be involved in GABAergic si...

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Detalles Bibliográficos
Autores principales: Lüffe, Teresa M., D’Orazio, Andrea, Bauer, Moritz, Gioga, Zoi, Schoeffler, Victoria, Lesch, Klaus-Peter, Romanos, Marcel, Drepper, Carsten, Lillesaar, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517032/
https://www.ncbi.nlm.nih.gov/pubmed/34650032
http://dx.doi.org/10.1038/s41398-021-01651-w