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Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

Ketamine, a racemic mixture of (S)-ketamine and (R)-ketamine enantiomers, has been used as an anesthetic, analgesic and more recently, as an antidepressant. However, ketamine has known abuse liability (the tendency of a drug to be used in non-medical situations due to its psychoactive effects), whic...

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Detalles Bibliográficos
Autores principales: Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517038/
https://www.ncbi.nlm.nih.gov/pubmed/33859356
http://dx.doi.org/10.1038/s41380-021-01093-2