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A Large Real-World Study on the Effectiveness of the Combined Inhibition of EGFR and MET in EGFR-Mutant Non-Small-Cell Lung Cancer After Development of EGFR-TKI Resistance

BACKGROUND: MET proto-oncogene amplification (amp) is an important mechanism underlying acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). However, the optimal treatment strategy after acquiring MET-amp-mediated EGFR-TKI resistance remains controversial...

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Detalles Bibliográficos
Autores principales: Liu, Li, Qu, Jingjing, Heng, Jianfu, Zhou, Chunhua, Xiong, Yi, Yang, Haiyan, Jiang, Wenjuan, Zeng, Liang, Zhu, Songlin, Zhang, Yongchang, Tan, Jiarong, Hu, Chengping, Deng, Pengbo, Yang, Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517073/
https://www.ncbi.nlm.nih.gov/pubmed/34660287
http://dx.doi.org/10.3389/fonc.2021.722039