HIF1A-AS2 induces osimertinib resistance in lung adenocarcinoma patients by regulating the miR-146b-5p/IL-6/STAT3 axis

Although epidermal growth factor receptor tyrosine kinase inhibitors (TKIs) show efficacy in lung adenocarcinoma (LUAD) patients, TKI resistance inevitably develops, limiting long-term results. Thus, there is an urgent need to address drug resistance in LUAD. Long non-coding RNA (lncRNA) HIF1A-AS2 c...

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Detalles Bibliográficos
Autores principales: Si, Jiahui, Ma, Yuanyuan, Lv, Chao, Hong, Yang, Tan, Hongyu, Yang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517096/
https://www.ncbi.nlm.nih.gov/pubmed/34703647
http://dx.doi.org/10.1016/j.omtn.2021.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517096/
https://www.ncbi.nlm.nih.gov/pubmed/34703647
http://dx.doi.org/10.1016/j.omtn.2021.09.003

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