Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum

Cocaine dependence is a chronic, relapsing disorder caused by lasting changes in the brain. Animal studies have identified cocaine-related alterations in striatal DNA methylation; however, it is unclear how methylation is related to cocaine dependence in humans. We generated methylomic profiles of t...

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Detalles Bibliográficos
Autores principales: Vaillancourt, Kathryn, Chen, Gang G., Fiori, Laura, Maussion, Gilles, Yerko, Volodymyr, Théroux, Jean-François, Ernst, Carl, Labonté, Benoit, Calipari, Erin, Nestler, Eric J., Nagy, Corina, Mechawar, Naguib, Mash, Deborah C., Turecki, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517202/
https://www.ncbi.nlm.nih.gov/pubmed/34693223
http://dx.doi.org/10.1016/j.isci.2021.103169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517202/
https://www.ncbi.nlm.nih.gov/pubmed/34693223
http://dx.doi.org/10.1016/j.isci.2021.103169

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